Immunization with the RgpA-Kgp Proteinase-Adhesin Complexes of Porphyromonas gingivalis Protects against Periodontal Bone Loss in the Rat Periodontitis Model

A major virulence factor of Porphyromonas gingivalis is the extracellular noncovalently associated complexes of Arg-X- and Lys-X-specific cysteine proteinases and adhesins designated the RgpA-Kgp complexes. In this study we investigated the ability of RgpA-Kgp as an immunogen to protect against P. g...

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Bibliographische Detailangaben
Hauptverfasser: Rajapakse, P. Sunethra, O'Brien-Simpson, Neil M., Slakeski, Nada, Hoffmann, Brigitte, Reynolds, Eric C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC127921/
https://ncbi.nlm.nih.gov/pubmed/11953385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.5.2480-2486.2002
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