Transient Requirement of the PrrA-PrrB Two-Component System for Early Intracellular Multiplication of Mycobacterium tuberculosis

Adaptive regulation of gene expression in response to environmental changes is a general property of bacterial pathogens. By screening an ordered transposon mutagenesis library of Mycobacterium tuberculosis, we have identified three mutants containing a transposon in the coding sequence or in the 5′...

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Bibliografiske detaljer
Main Authors: Ewann, Fanny, Jackson, Mary, Pethe, Kevin, Cooper, Andrea, Mielcarek, Nathalie, Ensergueix, Danielle, Gicquel, Brigitte, Locht, Camille, Supply, Philip
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC127906/
https://ncbi.nlm.nih.gov/pubmed/11953357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.5.2256-2263.2002
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