Transient Requirement of the PrrA-PrrB Two-Component System for Early Intracellular Multiplication of Mycobacterium tuberculosis

Adaptive regulation of gene expression in response to environmental changes is a general property of bacterial pathogens. By screening an ordered transposon mutagenesis library of Mycobacterium tuberculosis, we have identified three mutants containing a transposon in the coding sequence or in the 5′...

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Publicat a:	Infect Immun
Autors principals:	Ewann, Fanny, Jackson, Mary, Pethe, Kevin, Cooper, Andrea, Mielcarek, Nathalie, Ensergueix, Danielle, Gicquel, Brigitte, Locht, Camille, Supply, Philip
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2002
Matèries:	Molecular Pathogenesis
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127906/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11953357/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.5.2256-2263.2002
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