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A DNA Vaccine Encoding Lumazine Synthase from Brucella abortus Induces Protective Immunity in BALB/c Mice

This study was conducted to evaluate the immunogenicity of the Brucella abortus lumazine synthase (BLS) gene cloned into the pcDNA3 plasmid, which is driven by the cytomegalovirus promoter. Injection of plasmid DNA carrying the BLS gene (pcDNA-BLS) into BALB/c mice elicited both humoral and cellular...

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Bibliografiske detaljer
Main Authors: Velikovsky, Carlos A., Cassataro, Juliana, Giambartolomei, Guillermo H., Goldbaum, Fernando A., Estein, Silvia, Bowden, Raul A., Bruno, Laura, Fossati, Carlos A., Spitz, Moisés
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC127889/
https://ncbi.nlm.nih.gov/pubmed/11953389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.5.2507-2511.2002
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