A DNA Vaccine Encoding Lumazine Synthase from Brucella abortus Induces Protective Immunity in BALB/c Mice

This study was conducted to evaluate the immunogenicity of the Brucella abortus lumazine synthase (BLS) gene cloned into the pcDNA3 plasmid, which is driven by the cytomegalovirus promoter. Injection of plasmid DNA carrying the BLS gene (pcDNA-BLS) into BALB/c mice elicited both humoral and cellular...

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Detalhes bibliográficos
Main Authors: Velikovsky, Carlos A., Cassataro, Juliana, Giambartolomei, Guillermo H., Goldbaum, Fernando A., Estein, Silvia, Bowden, Raul A., Bruno, Laura, Fossati, Carlos A., Spitz, Moisés
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127889/
https://ncbi.nlm.nih.gov/pubmed/11953389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.5.2507-2511.2002
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