Pulmonary Inflammation Induced by Pseudomonas aeruginosa Lipopolysaccharide, Phospholipase C, and Exotoxin A: Role of Interferon Regulatory Factor 1

Chronic pulmonary infection with Pseudomonas aeruginosa is common in cystic fibrosis (CF) patients. P. aeruginosa lipopolysaccharide (LPS), phosholipase C (PLC), and exotoxin A (ETA) were evaluated for their ability to induce pulmonary inflammation in mice following intranasal inoculation. Both LPS...

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Detalhes bibliográficos
Main Authors: Wieland, Catharina W., Siegmund, Britta, Senaldi, Giorgio, Vasil, Michael L., Dinarello, Charles A., Fantuzzi, Giamila
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127789/
https://ncbi.nlm.nih.gov/pubmed/11854220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.3.1352-1358.2002
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