Pulmonary Inflammation Induced by Pseudomonas aeruginosa Lipopolysaccharide, Phospholipase C, and Exotoxin A: Role of Interferon Regulatory Factor 1

Chronic pulmonary infection with Pseudomonas aeruginosa is common in cystic fibrosis (CF) patients. P. aeruginosa lipopolysaccharide (LPS), phosholipase C (PLC), and exotoxin A (ETA) were evaluated for their ability to induce pulmonary inflammation in mice following intranasal inoculation. Both LPS...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Wieland, Catharina W., Siegmund, Britta, Senaldi, Giorgio, Vasil, Michael L., Dinarello, Charles A., Fantuzzi, Giamila
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2002
Schlagworte:	Host Response and Inflammation
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127789/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11854220/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.3.1352-1358.2002
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