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ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal
One of the major problems related with anticancer chemotherapy is resistance against anticancer drugs. The ATP-binding cassette (ABC) transporters are a family of transporter proteins that are responsible for drug resistance and a low bioavailability of drugs by pumping a variety of drugs out cells...
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| Format: | Artigo |
| Language: | Inglês |
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BioMed Central
2005
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1277830/ https://ncbi.nlm.nih.gov/pubmed/16202168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-5-30 |
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