Retrieving Biological Activity from LukF-PV Mutants Combined with Different S Components Implies Compatibility between the Stem Domains of These Staphylococcal Bicomponent Leucotoxins

Bicomponent leucotoxins, such as Panton-Valentine leucocidin, are composed of two classes of proteins, a class S protein such as LukS-PV, which bears the cell membrane binding function, and a class F protein such as LukF-PV, which interacts to form a bipartite hexameric pore. These leucotoxins induc...

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Detalhes bibliográficos
Main Authors: Werner, S., Colin, D. A., Coraiola, M., Menestrina, G., Monteil, H., Prévost, G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127755/
https://ncbi.nlm.nih.gov/pubmed/11854215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.3.1310-1318.2002
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