Increased Interleukin 4 (IL-4) Receptor Expression and IL-4-Induced Decrease in IL-12 Production by Langerhans Cells Infected with Leishmania major

Langerhans cells (LC) take up Leishmania major and are critical for the induction of the parasite-specific T-cell response. Their functional activities are regulated by cytokines. We analyzed whether infection of LC with L. major modulates the expression of their cytokine receptors. The expression o...

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Bibliographic Details
Main Authors: Moll, Heidrun, Scharner, Anabel, Kämpgen, Eckhart
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC127748/
https://ncbi.nlm.nih.gov/pubmed/11854255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.3.1627-1630.2002
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