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Influence of the Alternative σ(28) Factor on Virulence and Flagellum Expression of Legionella pneumophila

The fliA gene of Legionella pneumophila encoding the alternative σ(28) factor was inactivated by introducing a kanamycin resistance cassette. Electron microscopy and Western blot analysis revealed that the fliA mutant strain is aflagellate and expresses no flagellin. Reporter gene assays indicated t...

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Publicat a:Infect Immun
Autors principals: Heuner, Klaus, Dietrich, Claudia, Skriwan, Carina, Steinert, Michael, Hacker, Jörg
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127743/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11854250/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.3.1604-1608.2002
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