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Induction of T Helper Type 1 and 2 Responses to 19-Kilodalton Merozoite Surface Protein 1 in Vaccinated Healthy Volunteers and Adults Naturally Exposed to Malaria

Plasmodium falciparum malaria is a major cause of death in the tropics. The 19-kDa subunit of P. falciparum merozoite surface protein 1 (MSP-1(19)), a major blood stage vaccine candidate, is the target of cellular and humoral immune responses in animals and humans. In this phase I trial of MSP-1(19)...

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Hlavní autoři: Lee, Edwin A. M., Palmer, Dupeh R., Flanagan, Katie L., Reece, William H. H., Odhiambo, Kennedy, Marsh, Kevin, Pinder, Margaret, Gravenor, Michael B., Keitel, Wendy A., Kester, Kent E., Diggs, Carter, Kaslow, David, Apostolopoulos, V., Ballou, W. Ripley, Hill, Adrian V. S., Krzych, Urszula, Plebanski, Magdalena
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC127736/
https://ncbi.nlm.nih.gov/pubmed/11854228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.3.1417-1421.2002
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