Sensitivities of Human Monocytes and Epithelial Cells to Pneumolysin Are Different

The Streptococcus pneumoniae pore-forming toxin, pneumolysin, is an important virulence factor in pneumococcal pneumonia. The effect of pneumolysin on human lung epithelial and monocyte cell viability was compared. Pneumolysin caused a dose-dependent loss of viability of human lung epithelial (A549...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Hirst, Robert A., Yesilkaya, Hasan, Clitheroe, Edwin, Rutman, Andrew, Dufty, Nichola, Mitchell, Timothy J., O’Callaghan, Christopher, Andrew, Peter W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127723/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11796644/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.2.1017-1022.2002
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