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Phenotypic analysis of trypanothione synthetase knockdown in the African trypanosome
Trypanothione plays a pivotal role in defence against chemical and oxidant stress, thiol redox homoeostasis, ribonucleotide metabolism and drug resistance in parasitic kinetoplastids. In Trypanosoma brucei, trypanothione is synthesized from glutathione and spermidine by a single enzyme, TryS (trypan...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Portland Press Ltd.
2005
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1276942/ https://ncbi.nlm.nih.gov/pubmed/16008527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050911 |
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