Mutating His(29), His(125), His(133) or His(158) abolishes glycosylphosphatidylinositol-specific phospholipase D catalytic activity

Glycosylphosphatidylinositol (GPI)-specific phospholipase D (GPI-PLD) specifically cleaves GPIs. This phospholipase D is a secreted protein consisting of two domains: an N-terminal catalytic domain and a predicted C-terminal β-propeller. Although the biochemical properties of GPI-PLD have been exten...

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Detalhes bibliográficos
Main Authors: Raikwar, Nandita S., Bowen, Rosario F., Deeg, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276926/
https://ncbi.nlm.nih.gov/pubmed/15943582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050656
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