Differential biologic effects of CPD and 6-4PP UV-induced DNA damage on the induction of apoptosis and cell-cycle arrest

BACKGROUND: UV-induced damage can induce apoptosis or trigger DNA repair mechanisms. Minor DNA damage is thought to halt the cell cycle to allow effective repair, while more severe damage can induce an apoptotic program. Of the two major types of UV-induced DNA lesions, it has been reported that rep...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Lo, Hsin-Lung, Nakajima, Satoshi, Ma, Lisa, Walter, Barbara, Yasui, Akira, Ethell, Douglas W, Owen, Laurie B
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2005
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276790/
https://ncbi.nlm.nih.gov/pubmed/16236176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-5-135
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