Differential biologic effects of CPD and 6-4PP UV-induced DNA damage on the induction of apoptosis and cell-cycle arrest

BACKGROUND: UV-induced damage can induce apoptosis or trigger DNA repair mechanisms. Minor DNA damage is thought to halt the cell cycle to allow effective repair, while more severe damage can induce an apoptotic program. Of the two major types of UV-induced DNA lesions, it has been reported that rep...

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Autors principals: Lo, Hsin-Lung, Nakajima, Satoshi, Ma, Lisa, Walter, Barbara, Yasui, Akira, Ethell, Douglas W, Owen, Laurie B
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276790/
https://ncbi.nlm.nih.gov/pubmed/16236176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-5-135
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