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HLA-B*35-Restricted CD8(+)-T-Cell Epitope in Mycobacterium tuberculosis Rv2903c

Few human CD8(+) T-cell epitopes in mycobacterial antigens have been described to date. Here we have identified a novel HLA-B*35-restricted CD8(+) T-cell epitope in Mycobacterium tuberculosis Rv2903c based on a reverse immunogenetics approach. Peptide-specific CD8 T cells were able to kill M. tuberc...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Klein, Michèl R., Hammond, Abdulrahman S., Smith, Steve M., Jaye, Assan, Lukey, Pauline T., McAdam, Keith P. W. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2002
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127663/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11796635/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.2.981-984.2002
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