HLA-B*35-Restricted CD8(+)-T-Cell Epitope in Mycobacterium tuberculosis Rv2903c

Few human CD8(+) T-cell epitopes in mycobacterial antigens have been described to date. Here we have identified a novel HLA-B*35-restricted CD8(+) T-cell epitope in Mycobacterium tuberculosis Rv2903c based on a reverse immunogenetics approach. Peptide-specific CD8 T cells were able to kill M. tuberc...

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Detalhes bibliográficos
Main Authors: Klein, Michèl R., Hammond, Abdulrahman S., Smith, Steve M., Jaye, Assan, Lukey, Pauline T., McAdam, Keith P. W. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127663/
https://ncbi.nlm.nih.gov/pubmed/11796635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.2.981-984.2002
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