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Leishmania major Promastigotes Inhibit Dendritic Cell Motility In Vitro

Using an in vitro transwell migration assay, we have demonstrated that products secreted by Leishmania major promastigotes inhibit the motility of dendritic cells (DC) by up to 93%. Inhibition was dose dependent and reversible. By inhibiting DC migration in vivo, L. major may therefore subvert DC fr...

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Bibliografiske detaljer
Main Authors: Jebbari, Heather, Stagg, Andrew J., Davidson, Robert N., Knight, Stella C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC127657/
https://ncbi.nlm.nih.gov/pubmed/11796645
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