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l-Tryptophan-l-Kynurenine Pathway Metabolism Accelerated by Toxoplasma gondii Infection Is Abolished in Gamma Interferon-Gene-Deficient Mice: Cross-Regulation between Inducible Nitric Oxide Synthase and Indoleamine-2,3-Dioxygenase

l-Tryptophan degradation by indoleamine 2,3-dioxygenase (IDO) might have an important role in gamma interferon (IFN-γ)-induced antimicrobial effects. In the present study, the effects of Toxoplasma gondii infection on IDO were investigated by using wild-type and IFN-γ-gene-deficient (knockout) (IFN-...

詳細記述

保存先:
書誌詳細
主要な著者: Fujigaki, Suwako, Saito, Kuniaki, Takemura, Masao, Maekawa, Naoya, Yamada, Yasuhiro, Wada, Hisayasu, Seishima, Mitsuru
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC127656/
https://ncbi.nlm.nih.gov/pubmed/11796611
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