The role of TNF-α in the pathogenesis of type 1 diabetes in the nonobese diabetic mouse: Analysis of dendritic cell maturation

TNF-α has been linked to the development of type 1 diabetes (T1D). We previously reported that neonatal treatment of nonobese diabetic (NOD) mice with TNF-α accelerated the onset of T1D, whereas TNF-α blockade in the same time period resulted in a complete absence of diabetes. The mechanisms by whic...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lee, Li-Fen, Xu, Baohui, Michie, Sara A., Beilhack, Georg F., Warganich, Tibor, Turley, Shannon, McDevitt, Hugh O.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2005
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276103/
https://ncbi.nlm.nih.gov/pubmed/16247001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508122102
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