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A new generation of vectors with increased induction ratios by overimposing a second regulatory level by attenuation
A major drawback of regulated gene expression from vectors bearing strong promoters is the associated high basal expression level. Simple regulatory systems have an intrinsic limitation in the range of induction, and attempts to mutate promoters to reduce basal expression usually result in concomita...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1275594/ https://ncbi.nlm.nih.gov/pubmed/16260471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni168 |
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