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Alternative-splicing-based bicistronic vectors for ratio-controlled protein expression and application to recombinant antibody production

In the last decade polycistronic vectors have become essential tools for both basic science and gene therapy applications. In order to co-express heterologous polypeptides, different systems have been developed from Internal Ribosome Entry Site (IRES) based vectors to the use of the 2A peptide. Unfo...

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Detalhes bibliográficos
Main Authors: Fallot, Stéphanie, Ben Naya, Raouia, Hieblot, Corinne, Mondon, Philippe, Lacazette, Eric, Bouayadi, Khalil, Kharrat, Abdelhakim, Touriol, Christian, Prats, Hervé
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777421/
https://ncbi.nlm.nih.gov/pubmed/19729510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp716
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