Enhanced Accumulation and Changed Monomer Composition in Polyhydroxyalkanoate (PHA) Copolyester by In Vitro Evolution of Aeromonas caviae PHA Synthase

By in vitro evolution experiment, we have first succeeded in acquiring higher active mutants of a synthase that is a key enzyme essential for bacterial synthesis of biodegradable polyester, polyhydroxyalkanoate (PHA). Aeromonas caviae FA440 synthase, termed PhaC(Ac), was chosen as a good target for...

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Detalhes bibliográficos

Publicado no:	Appl Environ Microbiol
Principais autores:	Kichise, Tomoyasu, Taguchi, Seiichi, Doi, Yoshiharu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Physiology and Biotechnology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127549/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11976116/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.68.5.2411-2419.2002
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