Optimal Dose of Amoxicillin in Treatment of Otitis Media Caused by a Penicillin-Resistant Pneumococcus Strain in the Gerbil Model
Amoxicillin at doses of 0.2 to 5 mg/kg of body weight was administered for the treatment of pneumococcal otitis media in a gerbil model. Doses greater than or equal to 2.5 mg/kg, which resulted in concentrations in middle ear fluid of ≥1.4 μg/ml and concentrations in serum higher than the MIC (1 μg/...
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | Antimicrob Agents Chemother |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Microbiology (ASM)
2002
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127470/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11850273/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.3.859-862.2002 |
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