Pharmacokinetics, Excretion, and Mass Balance of Liposomal Amphotericin B (AmBisome) and Amphotericin B Deoxycholate in Humans

The pharmacokinetics, excretion, and mass balance of liposomal amphotericin B (AmBisome) (liposomal AMB) and the conventional formulation, AMB deoxycholate (AMB-DOC), were compared in a phase IV, open-label, parallel study in healthy volunteers. After a single 2-h infusion of 2 mg of liposomal AMB/k...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Bekersky, Ihor, Fielding, Robert M., Dressler, Dawna E., Lee, Jean W., Buell, Donald N., Walsh, Thomas J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Pharmacology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127462/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11850268/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.3.828-833.2002
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