Pharmacokinetics, Excretion, and Mass Balance of Liposomal Amphotericin B (AmBisome) and Amphotericin B Deoxycholate in Humans

The pharmacokinetics, excretion, and mass balance of liposomal amphotericin B (AmBisome) (liposomal AMB) and the conventional formulation, AMB deoxycholate (AMB-DOC), were compared in a phase IV, open-label, parallel study in healthy volunteers. After a single 2-h infusion of 2 mg of liposomal AMB/k...

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Main Authors: Bekersky, Ihor, Fielding, Robert M., Dressler, Dawna E., Lee, Jean W., Buell, Donald N., Walsh, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC127462/
https://ncbi.nlm.nih.gov/pubmed/11850268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.3.828-833.2002
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