Immunomodulatory Effect of Zidovudine (ZDV) on Cytotoxic T Lymphocytes Previously Exposed to ZDV

In a previous study, zidovudine (ZDV) was shown to cause a concentration-dependent inhibition of antigen-specific cytotoxic T-lymphocyte (CTL) clonal expansion (S. Francke, C. G. Orosz, K. A. Hayes, and L. E. Mathes, Antimicrob. Agents Chemother. 44:1900-1905, 2000). However, this suppressive effect...

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Main Authors: Francke, Sabine, Orosz, Charles G., Hsu, Jason, Mathes, Lawrence E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC127449/
https://ncbi.nlm.nih.gov/pubmed/12183239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.9.2865-2871.2002
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