The Antifungal Echinocandin Caspofungin Acetate Kills Growing Cells of Aspergillus fumigatus In Vitro

Caspofungin acetate is an antifungal antibiotic that inhibits synthesis of 1,3-β-d-glucan, an essential component of the fungal cell wall. While caspofungin causes cell death in yeasts and dimorphic fungi such as Candida albicans, its effect on Aspergillus fumigatus is less well understood. We used...

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Bibliographische Detailangaben
Hauptverfasser: Bowman, J. C., Hicks, P. Scott, Kurtz, M. B., Rosen, H., Schmatz, D. M., Liberator, P. A., Douglas, C. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Mechanisms of Action: Physiological Effects
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC127409/
https://ncbi.nlm.nih.gov/pubmed/12183260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.9.3001-3012.2002
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