Intranasal Immunization Strategy To Impede Pilin-Mediated Binding of Pseudomonas aeruginosa to Airway Epithelial Cells

Prevention of pulmonary Pseudomonas aeruginosa infections represents a critical unmet medical need for cystic fibrosis (CF) patients. We have examined the tenet that a mucosal immunization approach can reduce interactions of a piliated form of this opportunistic pathogen with respiratory epithelial...

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Autors principals: Hsieh, Jennifer C., Tham, Doris M., Feng, Weijun, Huang, Fan, Embaie, Selamawit, Liu, Keyi, Dean, Deborah, Hertle, Ralf, FitzGerald, David J., Mrsny, Randall J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1273878/
https://ncbi.nlm.nih.gov/pubmed/16239575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.11.7705-7717.2005
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