Extrusion of Penem Antibiotics by Multicomponent Efflux Systems MexAB-OprM, MexCD-OprJ, and MexXY-OprM of Pseudomonas aeruginosa

The high intrinsic penem resistance of Pseudomonas aeruginosa is due to the interplay among the outer membrane barrier, the active efflux system MexAB-OprM, and AmpC β-lactamase. We studied the roles of two other efflux systems, MexCD-OprJ and MexXY-OprM, in penem resistance by overexpressing each s...

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Опубликовано в::	Antimicrob Agents Chemother
Главные авторы:	Okamoto, Kiyomi, Gotoh, Naomasa, Nishino, Takeshi
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2002
Предметы:	Mechanisms of Resistance
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127373/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12121960/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.8.2696-2699.2002
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