Inhibition of Cyclin-Dependent Kinase 1 by Purines and Pyrrolo[2,3-d]Pyrimidines Does Not Correlate with Antiviral Activity

We have previously shown that a series of nonnucleoside pyrrolo[2,3-d]pyrimidines selectively inhibit the replication of herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (HCMV). These compounds act at the immediate-early or early stage of HCMV replication and have antiviral properties s...

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Detalhes bibliográficos
Main Authors: Evers, David L., Breitenbach, Julie M., Borysko, Katherine Z., Townsend, Leroy B., Drach, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127371/
https://ncbi.nlm.nih.gov/pubmed/12121920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.8.2470-2476.2002
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