Human Cytomegalovirus Resistance to Deoxyribosylindole Nucleosides Maps to a Transversion Mutation in the Terminase Subunit-Encoding Gene UL89

Human cytomegalovirus (HCMV) infection can cause severe illnesses, including encephalopathy and mental retardation, in immunocompromised and immunologically immature patients. Current pharmacotherapies for treating systemic HCMV infections include ganciclovir, cidofovir, and foscarnet. However, long...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Gentry, Brian G., Phan, Quang, Hall, Ellie D., Breitenbach, Julie M., Borysko, Katherine Z., Kamil, Jeremy P., Townsend, Leroy B., Drach, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291354/
https://ncbi.nlm.nih.gov/pubmed/25348532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03686-14
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