Human Cytomegalovirus Resistance to Deoxyribosylindole Nucleosides Maps to a Transversion Mutation in the Terminase Subunit-Encoding Gene UL89

Human cytomegalovirus (HCMV) infection can cause severe illnesses, including encephalopathy and mental retardation, in immunocompromised and immunologically immature patients. Current pharmacotherapies for treating systemic HCMV infections include ganciclovir, cidofovir, and foscarnet. However, long...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Gentry, Brian G., Phan, Quang, Hall, Ellie D., Breitenbach, Julie M., Borysko, Katherine Z., Kamil, Jeremy P., Townsend, Leroy B., Drach, John C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
Ämnen:
Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291354/
https://ncbi.nlm.nih.gov/pubmed/25348532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03686-14
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