Overexpression of Sbe2p, a Golgi Protein, Results in Resistance to Caspofungin in Saccharomyces cerevisiae
Caspofungin inhibits the synthesis of 1, 3-β-d-glucan, an essential cell wall target in fungi. Genetic studies in the model yeast Saccharomyces cerevisiae have shown that mutations in FKS1 and FKS2 genes result in caspofungin resistance. However, direct demonstration of the role of gene overexpressi...
Sparad:
| I publikationen: | Antimicrob Agents Chemother |
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| Huvudupphov: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
American Society for Microbiology (ASM)
2002
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127366/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12121919/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.8.2462-2469.2002 |
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