Novel Nucleoside Analogue MCC-478 (LY582563) Is Effective against Wild-Type or Lamivudine-Resistant Hepatitis B Virus

The emergence of resistant hepatitis B virus (HBV) with the L528M mutation and/or the M552V and M552I mutations in the polymerase gene following long-term lamivudine treatment is becoming an important clinical problem. The aim of this study was to investigate the susceptibility of wild-type and lami...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Ono-Nita, Suzane Kioko, Kato, Naoya, Shiratori, Yasushi, Carrilho, Flair José, Omata, Masao
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Antiviral Agents
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127322/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12121939/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.8.2602-2605.2002
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