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Novel Nucleoside Analogue MCC-478 (LY582563) Is Effective against Wild-Type or Lamivudine-Resistant Hepatitis B Virus

The emergence of resistant hepatitis B virus (HBV) with the L528M mutation and/or the M552V and M552I mutations in the polymerase gene following long-term lamivudine treatment is becoming an important clinical problem. The aim of this study was to investigate the susceptibility of wild-type and lami...

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Hlavní autoři: Ono-Nita, Suzane Kioko, Kato, Naoya, Shiratori, Yasushi, Carrilho, Flair José, Omata, Masao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC127322/
https://ncbi.nlm.nih.gov/pubmed/12121939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.8.2602-2605.2002
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