Amino Acid Residues Essential for Function of the MexF Efflux Pump Protein of Pseudomonas aeruginosa

At least four broad-spectrum efflux pumps (Mex) are involved in elevated intrinsic antibiotic resistance as well as in acquired multidrug resistance in Pseudomonas aeruginosa. Substrate specificity of the Mex pumps has been shown to be determined by the cytoplasmic membrane component (MexB, MexD, Me...

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Bibliographic Details
Main Authors: Ramos Aires, Julio, Pechère, Jean-Claude, Van Delden, Christian, Köhler, Thilo
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC127300/
https://ncbi.nlm.nih.gov/pubmed/12069970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.7.2169-2173.2002
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