Inhibition of Penicillinase by Epigallocatechin Gallate Resulting in Restoration of Antibacterial Activity of Penicillin against Penicillinase-Producing Staphylococcus aureus

The combination of epigallocatechin gallate (EGCg, a main constituent of tea catechins) with penicillin showed synergism against 21 clinical isolates of penicillinase-producing Staphylococcus aureus. Besides binding directly to peptidoglycan, the inhibition of penicillinase activity by EGCg is respo...

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Detalhes bibliográficos
Main Authors: Zhao, Wei-Hua, Hu, Zhi-Qing, Hara, Yukihiko, Shimamura, Tadakatsu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127279/
https://ncbi.nlm.nih.gov/pubmed/12069986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.7.2266-2268.2002
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