Inhibition of Penicillinase by Epigallocatechin Gallate Resulting in Restoration of Antibacterial Activity of Penicillin against Penicillinase-Producing Staphylococcus aureus

The combination of epigallocatechin gallate (EGCg, a main constituent of tea catechins) with penicillin showed synergism against 21 clinical isolates of penicillinase-producing Staphylococcus aureus. Besides binding directly to peptidoglycan, the inhibition of penicillinase activity by EGCg is respo...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Zhao, Wei-Hua, Hu, Zhi-Qing, Hara, Yukihiko, Shimamura, Tadakatsu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Mechanisms of Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127279/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12069986/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.7.2266-2268.2002
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