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Marked Potentiation of Activity of β-Lactams against Methicillin-Resistant Staphylococcus aureus by Corilagin

We found that an extract of Arctostaphylos uva-ursi markedly reduced the MICs of β-lactam antibiotics, such as oxacillin and cefmetazole, against methicillin-resistant Staphylococcus aureus. We isolated the effective compound and identified it as corilagin. Corilagin reduced the MICs of various β-la...

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Detalhes bibliográficos
Main Authors: Shimizu, Masato, Shiota, Sumiko, Mizushima, Tohru, Ito, Hideyuki, Hatano, Tsutomu, Yoshida, Takashi, Tsuchiya, Tomofusa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90804/
https://ncbi.nlm.nih.gov/pubmed/11600378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.11.3198-3201.2001
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