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Mefloquine and New Related Compounds Target the F(0) Complex of the F(0)F(1) H(+)-ATPase of Streptococcus pneumoniae

The activities of mefloquine (MFL) and related compounds against previously characterized Streptococcus pneumoniae strains carrying defined amino acid substitutions in the c subunit of the F(0)F(1) H(+)-ATPase were studied. In addition, a series of MFL-resistant (Mfl(r)) strains were isolated and ch...

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Detalhes bibliográficos
Main Authors: Martín-Galiano, Antonio Javier, Gorgojo, Begoña, Kunin, Calvin M., de la Campa, Adela G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127268/
https://ncbi.nlm.nih.gov/pubmed/12019076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.6.1680-1687.2002
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