Mefloquine and New Related Compounds Target the F(0) Complex of the F(0)F(1) H(+)-ATPase of Streptococcus pneumoniae

The activities of mefloquine (MFL) and related compounds against previously characterized Streptococcus pneumoniae strains carrying defined amino acid substitutions in the c subunit of the F(0)F(1) H(+)-ATPase were studied. In addition, a series of MFL-resistant (Mfl(r)) strains were isolated and ch...

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Cyhoeddwyd yn:	Antimicrob Agents Chemother
Prif Awduron:	Martín-Galiano, Antonio Javier, Gorgojo, Begoña, Kunin, Calvin M., de la Campa, Adela G.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	American Society for Microbiology (ASM) 2002
Pynciau:	Mechanisms of Action: Physiological Effects
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127268/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12019076/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.6.1680-1687.2002
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