In Vitro Activities of Novel Nonfluorinated Quinolones PGE 9262932 and PGE 9509924 against Clinical Isolates of Staphylococcus aureus and Streptococcus pneumoniae with Defined Mutations in DNA Gyrase and Topoisomerase IV

Two 8-methoxy nonfluorinated quinolones (NFQs), PGE 9262932 and PGE 9509924, were tested against contemporary clinical isolates of Staphylococcus aureus (n = 122) and Streptococcus pneumoniae (n = 69) with genetically defined quinolone resistance-determining regions (QRDRs). For S. aureus isolates w...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Jones, Mark E., Critchley, Ian A., Karlowsky, James A., Blosser-Middleton, Renée S., Schmitz, Franz-Josef, Thornsberry, Clyde, Sahm, Daniel F.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2002
Materias:	Susceptibility
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127266/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12019071/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.6.1651-1657.2002
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