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30S Ribosomal Subunit Assembly Is a Target for Inhibition by Aminoglycosides in Escherichia coli
The aminoglycosides paromomycin and neomycin were examined in Escherichia coli cells for an inhibitory effect on 30S ribosomal subunit assembly. Both compounds inhibited the growth rate, viable cell number, and protein synthesis rate with similar 50% inhibitory concentrations. Each drug also showed...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2002
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC127183/ https://ncbi.nlm.nih.gov/pubmed/11959595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1546-1549.2002 |
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