30S Ribosomal Subunit Assembly Is a Target for Inhibition by Aminoglycosides in Escherichia coli

The aminoglycosides paromomycin and neomycin were examined in Escherichia coli cells for an inhibitory effect on 30S ribosomal subunit assembly. Both compounds inhibited the growth rate, viable cell number, and protein synthesis rate with similar 50% inhibitory concentrations. Each drug also showed...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Mehta, Roopal, Champney, W. Scott
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2002
Fag:	Mechanisms of Resistance
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127183/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11959595/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.5.1546-1549.2002
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