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Molecular clearance of ataxin-3 is regulated by a mammalian E4

Insoluble aggregates of polyglutamine-containing proteins are usually conjugated with ubiquitin in neurons of individuals with polyglutamine diseases. We now show that ataxin-3, in which the abnormal expansion of a polyglutamine tract is responsible for spinocerebellar ataxia type 3 (SCA3), undergoe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Matsumoto, Masaki, Yada, Masayoshi, Hatakeyama, Shigetsugu, Ishimoto, Hiroshi, Tanimura, Teiichi, Tsuji, Shoji, Kakizuka, Akira, Kitagawa, Masatoshi, Nakayama, Keiichi I
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1271811/
https://ncbi.nlm.nih.gov/pubmed/14749733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600081
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