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Characterization of Wild-Type and Cidofovir-Resistant Strains of Camelpox, Cowpox, Monkeypox, and Vaccinia Viruses

Cidofovir {[(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine] [HPMPC]}-resistant forms of camelpox, cowpox, monkeypox, and vaccinia viruses were developed by prolonged passage in Vero 76 cells in the presence of drug. Eight- to 27-fold-higher concentrations of cidofovir were required to inhibit t...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Smee, Donald F., Sidwell, Robert W., Kefauver, Debbie, Bray, Mike, Huggins, John W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127179/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11959564/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.5.1329-1335.2002
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