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Phosphorylation of MRF4 transactivation domain by p38 mediates repression of specific myogenic genes
Skeletal myogenesis is associated with the activation of four muscle regulatory factors (MRFs): Myf5, MyoD, Myogenin and MRF4. Here we report that p38 mitogen-activated protein kinase represses the transcriptional activity of MRF4 (involved in late stages of myogenesis), resulting in downregulation...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1271762/ https://ncbi.nlm.nih.gov/pubmed/14739931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600056 |
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