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Phosphorylation of MRF4 transactivation domain by p38 mediates repression of specific myogenic genes

Skeletal myogenesis is associated with the activation of four muscle regulatory factors (MRFs): Myf5, MyoD, Myogenin and MRF4. Here we report that p38 mitogen-activated protein kinase represses the transcriptional activity of MRF4 (involved in late stages of myogenesis), resulting in downregulation...

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Bibliografski detalji
Glavni autori: Suelves, Mònica, Lluís, Frederic, Ruiz, Vanessa, Nebreda, Angel R, Muñoz-Cánoves, Pura
Format: Artigo
Jezik:Inglês
Izdano: 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1271762/
https://ncbi.nlm.nih.gov/pubmed/14739931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600056
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