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Crystal structures of histone Sin mutant nucleosomes reveal altered protein–DNA interactions
Here we describe 11 crystal structures of nucleosome core particles containing individual point mutations in the structured regions of histones H3 and H4. The mutated residues are located at the two protein–DNA interfaces flanking the nucleosomal dyad. Five of the mutations partially restore the in...
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| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2004
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1271754/ https://ncbi.nlm.nih.gov/pubmed/14739929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600046 |
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