rpoB Mutation Conferring Rifampin Resistance in Streptococcus pyogenes

Streptococcus pyogenes BM4478 and Staphylococcus aureus BM4479 were isolated from a patient undergoing rifampin therapy. High-level resistance to rifampin was due to the following mutations in the rpoB gene: Ser(522)Leu in strain BM4478 and His(526)Asn and Ser(574)Leu in strain BM4479.

Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Aubry-Damon, Hélène, Galimand, Marc, Gerbaud, Guy, Courvalin, Patrice
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2002
Fag:	Mechanisms of Resistance
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127170/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11959602/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.5.1571-1573.2002
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